Lead discovery

InhibOx Updates Partial Charges for DUD Molecules

Submitted by InhibOx on July 6, 2010 - 21:00

Cloud Computing and Drug Discovery article published in Projects Magazine

Submitted by InhibOx on April 10, 2010 - 06:00

Oxford, UK - 9th April 2010

InhibOx's Paul Finn discusses the potential of on-demand hardware and Software as a Service delivery mechanisms to transform drug discovery research in a recent article for Projects Magazine, a leading research and development publication in the areas of science and technology.

Lead Identification

As part of its DrugFinder initiative, InhibOx collaborated with the group of Dr. Angela Russell of the Departments of Pharmacology and Chemistry, at the University of Oxford. Taking an oncology kinase target as its starting point, InhibOx performed virtual screening of CSpace, using our database of commercially available molecules and our proprietary software platform to identify inhibitors for experimental screening. 

AutoDock helps tackle two AIDS targets, HIV Protease and HIV Integrase

Submitted by InhibOx on March 8, 2010 - 19:29

Oxford, UK — 11th March, 2010.

The Scripps Research Institute and the FightAIDS@Home project announce new publications and the discovery of two new anti-HIV compounds.

A recent publication in the Journal of Molecular Biology, on which leading InhibOx scientist Dr. Garrett M. Morris is a co-author, describes a dynamic model of HIV integrase inhibition and drug resistance.  This work employed the ligand-protein docking program, AutoDock, of which Garrett is a key developer.

Intelligensys and InhibOx Apply Proven Formulation Approaches to Improve Lead Discovery Efficiency

Submitted by InhibOx on February 8, 2010 - 16:00

Oxford and Stokesley, UK — 8th February 2010

InhibOx Ltd (Oxford, UK) and Intelligensys Ltd (Stokesley, North Yorkshire, UK) announce a partnership to apply advanced machine learning approaches, already successful in formulation design, to improve virtual screening and computer-aided drug design (CADD) efficiency.

DrugFinder